Searchable abstracts of presentations at key conferences in endocrinology

ea0029s18.1 | Molecular mechanisms in autoimmune thyroid disease | ICEECE2012

Predictors of relapse of Graves’ disease after antithyroid drug withdrawal

Wang P. , Chen I. , Juo S. , Hsi E. , Liu R. , Hsieh C.

For patients with GravesÂ’ disease (GD), the primary goal of antithyroid drug therapy is to temporarily restore the patient to the euthyroid state and wait for a subsequent remission of the disease. This study sought to identify the predictive markers for the relapse of disease.To do this, we studied 262 GD patients with long enough follow-up after drug withdrawal to determine treatment outcome. The patients were divided into three groups by time of ...

ea0026p457 | Thyroid cancer | ECE2011

Reversine, an anti-cancer candidate, induces cell cycle arrest and apoptosis in human thyroid cancer

Lee Ying-Ray , Hua Shih-Che , Chen Shu-Hsin , Lu Chieh-Hsiang , Yu Hui-I , Chen Hau-Ren , Chang Tien-Chun

Thyroid cancer is the most prevalent cancer among endocrine malignancies. Surgical resection combined with radioactive iodine therapy has been proved effective in treating differentiated thyroid cancer, including papillary and follicular thyroid cancers. However, regarding metastatic poorly differentiated or anaplastic thyroid cancers, there have been no available effective treatment modalities. The genomic instability, such as chromosome aneupolidy, represents a hallmark of s...